NAC (N-Acetylcysteine) Supplementation and COVID-19

NAC (N-Acetylcysteine) Supplementation and COVID-19
Dr. Seheult of

LINK: NIH.GOV n-acetylcysteine (NAC): A potential therapeutic agent for SARS-CoV-2

LINK: NIH.GOV Therapeutic blockade of inflammation in severe COVID-19 infection with intravenous n-acetylcysteine (NAC)

LINK: N-acetylcysteine as a potential treatment for novel coronavirus disease 2019

Dr. Seheult on COVID-19 as an Endothelial Disease

Dr. Seheult: Coronavirus Pandemic Update 63: Is COVID-19 a Disease of the Endothelium (Blood Vessels and Clots)

This helps to explain why COVID-19 is causing strokes in younger patients.

Large Vessel Strokes in Younger Patients Tied to COVID-19

Five COVID-19 patients ages 33 to 49 developed acute ischemic large-vessel stroke, data from a New York City health system showed.

Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young

We report five cases of large-vessel stroke in patients younger than 50 years of age who presented to our health system in New York City. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was diagnosed in all five patients.

Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19

Using an observational database from 169 hospitals in Asia, Europe, and North America, we evaluated the relationship of cardiovascular disease and drug therapy with in-hospital death among hospitalized patients with Covid-19 who were admitted between December 20, 2019, and March 15, 2020, and were recorded in the Surgical Outcomes Collaborative registry as having either died in the hospital or survived to discharge as of March 28, 2020.

Hydroxychloroquine Has about 90 Percent Chance of Helping COVID-19 Patients

Hydroxychloroquine Has about 90 Percent Chance of Helping COVID-19 Patients

States Association of American Physicians and Surgeons (AAPS)

To date, the total number of reported patients treated with HCQ, with or without zinc and the widely used antibiotic azithromycin, is 2,333, writes AAPS, in observational data from China, France, South Korea, Algeria, and the U.S. Of these, 2,137 or 91.6 percent improved clinically. There were 63 deaths, all but 11 in a single retrospective report from the Veterans Administration where the patients were severely ill.

Sequential CQ / HCQ Research Papers and Reports

January to April 20, 2020

Executive Summary Interpretation of the Data In This Report

The HCQ-AZ combination, when started immediately after diagnosis, appears to be a safe and efficient treatment for COVID-19, with a mortality rate of 0.5% in elderly patients. It avoids worsening and clears virus persistence and contagious infectivity in most cases.

The probabilities of clinical success using

hydroxychloroquine with or without azithromycin +/- zinc

against the novel betacoronavirus, SARS-CoV-2

(Use the link below to access the table)

Why Is Hydroxychloroquine Being Demonized?

By preventing the use of hydroxychloroquine in combination with zinc, lives are being lost.

Prior to March 2020, hydroxychloroquine was considered relatively safe, with a rare risk of arrhythmia, but not death.

Hydroxychloroquine, originally used as an antimalarial agent, has beneficial effects on mucocutaneous symptoms in systemic lupus erythematosus. It is also used for the skin rash of discoid lupus erythematosus. A number of rare but serious adverse reactions can occur with its use and are usually associated with long-term therapy.

Beginning in March 2020, after hydroxychloroquine in conjunction with zinc was identified as a possible treatment for COVID-19, hydroxychloroquine suddenly became deadly:

Antimalarials widely used against COVID-19 heighten risk of cardiac arrest.
FDA: Improper use of hydroxychloroquine, chloroquine for COVID-19 may increase risk for arrhythmias, death
Small chloroquine study ends early in Brazil due to deaths

A warning to those considering combination therapy with hydroxychloroquine (HCQ) for COVID-19: individually, some medications being considered have been known to put users at risk of sudden cardiac death, major U.S. medical societies said.

In response to the new hysteria about the danger of hydroxychloroquine, the American College of Cardiology wrote this:

Chloroquine, and its more contemporary derivative hydroxychloroquine, have remained in clinical use for more than a half-century as an effective therapy for treatment of some malarias, lupus, and rheumatoid arthritis. Data show inhibition of iKr and resultant mild QT prolongation associated with both agents.
Despite these suggestive findings, several hundred million courses of chloroquine have been used worldwide making it one of the most widely used drugs in history, without reports of arrhythmic death under World Health Organization surveillance.

COVID-19 Update 59: Dr. Seheult’s Daily Regimen

Coronavirus Pandemic Update 59: Dr. Seheult’s Daily Regimen (Vitamin D, C, Zinc, Quercetin, NAC)

What supplements Dr. Seheult takes daily to help protect against COVID-19:

Vitamin C
Vitamin D: 2500 IU or 62.5 mcg per day
Zinc 50 mg per day for a short period of time
Quercetin 500 mg 2 times per day
NAC (N acetyl Cysteine) 600 mg 2 times per day

Dr. Seheult gives detailed information in the video.

Personal Experience: How I Beat COVID-19

Gene Dellasala of Audioholics tells how he beat COVID-19 taking hydroxychloroquine and azithromycin and zinc and talks about the side effects.

Dr. Zelenko’s prescription for COVID-19

1- hydroxychloroquine 200mg twice a day for 5 days
2- azithromycin 500mg once a day for five days (people with heart problems should consider a different antibiotic)
3- zinc sulfate 220mg once a day for five days

WebMD: COVID-19 Clinical Trials to test cures and prevention

WebMD presents information on a number of clinical trials taking place around the world which are testing ways to cure and prevent COVID-19.

Clinical trials are testing hydroxychloroquine and zinc, vitamins C and D, HIV drugs Lopinavir and Ritonavir, and a mouth spray containing the antiseptic ARMS-I.

Most of the clinical trials will have results this summer.

WebMD on COVID-19 clinical trials

Medmastery: Scientific explanations of how zinc is helped to enter the cell by hydroxychloroquine where the zinc then prevents virus replication:

JJ Medicine: Chloroquine, Hydroxychloroquine & SARS-CoV-2 (COVID-19): Mechanism & Overview of Anti-Viral Effects

COVID-19: Hydroxychloroquine May NOT Work Without Taking Zinc

COVID-19: Hydroxychloroquine May NOT Work Without Taking Zinc

Dr. Eric Berg DC: Here is something really important you need to know about hydroxychloroquine and zinc, and what the combination might do for COVID-19.

> More Videos from Dr. Berg


Dr. Cardillo with Mend Urgent Care in Sherman Oaks says using hydroxychloroquine with zinc appears to be working in the handful of patients he has prescribed it to.

“It was actually the hydroxychloroquine opening up a channel in the cellular membranes allowing zinc to come into the cells,” he said, “And we do know high levels of zinc inside of the cell that’s infected with the virus shuts down that viral replication machinery.”

He also gave patients azithromycin, an antibiotic most of us know as a Z-pack, to treat possible subsequent bacterial infections.

Of the 95 patients who have tested positive under Dr. Cardillo’s care, five had symptoms serious enough for him to prescribe the combination treatment. All were outpatient.

He said, “The other 90 people did very well on their own. No treatment whatsoever.”

He says chloroquine should not be taken as a preventative and it should not be given to people with mild symptoms. For some it can cause an irregular heartbeat that could be dangerous.

“This regimen has to be used on a hospital level, it has to be managed by physicians for people who are getting very sick,” he said. “The basic tenet or principle of medicine is to do no harm.”

N.Y. doctor’s success treating COVID-19 patients reaches the White House

News of Dr. Vladimir Zelenko’s success treating COVID-19 patients reaches the White House.

Zero Deaths, Zero Intubation

Dr. Zelenko’s prescription for COVID-19

1- hydroxychloroquine 200mg twice a day for 5 days
2- azithromycin 500mg once a day for five days (people with heart problems should consider a different antibiotic)
3- zinc sulfate 220mg once a day for five days

In related news:

French pharmaceutical giant Sanofi said Friday it would offer 100 million doses of hydroxychloroquine, which it sells under the brand name Plaquenil, a treatment for rheumatoid arthritis and lupus, to governments worldwide if studies show it can safely to be used to treat COVID-19 patients.
Sanofi offers to donate 100 million doses of hydroxychloroquine

LANSING, MI — Democratic state representative Karen Whitsett from Detroit is crediting hydroxychloroquine — and Republican President Donald Trump who touted the drug — for saving her in her battle with the coronavirus.
Democratic state rep thanks Trump & hydroxychloroquine for saving her in her battle with the coronavirus.

photo of Michigan State Representative Karen Whitsett
Michigan State Representative Karen Whitsett